I am doing a frame off of a 75 Bronco. I will be running a Blueprint 306 w/Sniper. Do I need to run a tank vent on this application. If so how?

You will at the very least want a vented gas cap. If you can tie into your original, if still in place, vent system, that would be good. Otherwise, some will run a vent hose with a check valve up into the tail-light housing. To allow air in, but not fumes or fuel out.